Surface-Enhanced Laser Desorption / Ionization (SELDI)is an ionization method in mass spectrometry that used for the analysis of protein mixtures.
SELDI is typically used with time-of-flight mass spectrometers and is used to detect proteins in tissue samples, blood, urine, or other clinical sapmles.
Comparison of protein levels between patients with and without a disease can be used for biomarker discovery.











